Pharmaceutical Product Positioning

Example Project: Investigate a Pharmaceutical Product's Efficacy

We were involved in a project investigating whether a pharmaceutical product for diabetes treatment resulted in liver toxicity. We were asked to review medical claims data from millions of patients, isolate diabetic patients taking one of several types of diabetes products, and determine whether outcomes for patients on one diabetes product were different than for patients on other diabetes products. We developed an appropriate methodology and the patient outcome measures.

Experience

• Partnered with many of the leading pharmaceutical manufacturers and supported clinical trial Phase 3 work efforts and Phase 4 pharmacoeconomic research, including the following manufacturers--Bristol-Myers Squibb, Wyeth Ayerst, SmithKline Beecham, AstraZeneca, GlaxoWellcome, Eli Lilly, Warner Lambert, and Johnson and Johnson.

• Performed pioneering work in pharmacoeconomic research to define patient outcome measures using medical claims data, including the following--early termination of product use, monotherapy versus combination therapy, drug switching, drug titration, and adverse medical side effects (e.g., gastrointestinal events, renal events).

• Developed a patented system that integrates all inpatient, outpatient, ambulatory, and prescription drug claims data into episodes of care by medical condition (Cave et al, Patent Number 5,970,463). The system was designed to perform pharmacoeconomic research.

• Obtained from the University of California, Los Angeles, a Ph.D. in Health Planning and Policy, and a Masters in Public Health in infectious disease epidemiology--providing a strong clinical, statistical, and methodological background.

Represented Industries and Organizations

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